4,4'-methylenebis[2-chloroaniline]

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• Home page

• General Information

  • Identification

  • Compositions

    • 4,4’-Methylene bis (2-chloroaniline)
    • 4,4'-methylenebis[2-chloroaniline]
    • 4,4'-methylenebis[2-chloroaniline]
    • 4,4'-methylenebis[2-chloroaniline]
    • 3,3'-Dichloro-4,4'-diaminodiphenylmethane
    • 4,4'-methylenebis[2-chloroaniline]

• Classification and Labelling

  • GHS

    • 4,4'-methylenebis[2-chloroaniline]
    • 4,4'-methylenebis[2-chloroaniline]

  • DSD - DPD

    • 4,4’-Methylene bis (2-chloroaniline)
    • 4,4’-Methylene bis (2-chloroaniline)

• Manufacture, Use & Exposure

  • Identified uses
  • Uses advised against

• PBT assessment

  • (JS Member) PBT assessment.001

• Physical and chemical properties

  • Appearance/physical state/colour

    • Other WoE Appearance/physical state/colour.001
    • Other WoE Appearance/physical state/colour.002

  • Melting point/freezing point

    • Exp Key Melting point/freezing point.001

  • Boiling point

    • NS NS Boiling point.001

  • Density

    • Exp Key Density.001

  • Particle size distribution (Granulometry)

    • NS NS Particle size distribution (Granulometry).001

  • Vapour pressure

    • Exp Key Vapour pressure.001

  • Partition coefficient

    • Exp Key Partition coefficient.001

  • Water solubility

    • Exp Key Water solubility.001

  • Surface tension

    • Exp Key Surface tension.001

  • Flash point

    • NS NS Flash point.001

  • Auto flammability

    • NS NS Auto flammability.001

  • Flammability

    • Exp Key Flammability.001
    • Other Key Flammability.002
    • Other Key Flammability.003

  • Explosiveness

    • Other Key Explosiveness.001

  • Oxidising properties

    • Other Key Oxidising properties.001

  • Stability in organic solvents and identity of relevant degradation products

    • NS NS Stability in organic solvents and identity of relevant degradation products.001

  • Dissociation constant

    • NS NS Dissociation constant.001
    • QSAR Supporting Dissociation constant.002

  • Viscosity

    • NS NS Viscosity.001

• Environmental fate and pathways

  • Stability

    • Hydrolysis

      • Exp Key Hydrolysis.001

  • Biodegradation

    • Biodegradation in water: screening tests

      • Exp WoE Biodegradation in water: screening tests.001
      • QSAR WoE Biodegradation in water: screening tests.002

    • Biodegradation in water and sediment: simulation tests

      • NS NS Biodegradation in water and sediment: simulation tests.001

    • Biodegradation in soil

      • Exp Supporting Biodegradation in soil.001
      • NS NS Biodegradation in soil.002

  • Bioaccumulation

    • Bioaccumulation: aquatic / sediment

      • Other WoE Bioaccumulation: aquatic / sediment.001
      • QSAR WoE Bioaccumulation: aquatic / sediment.002

    • Bioaccumulation: terrestrial

      • Exp Supporting Bioaccumulation: terrestrial.001

  • Transport and distribution

    • Adsorption / desorption

      • Exp Key Adsorption / desorption.001
      • Exp Supporting Adsorption / desorption.002

• Ecotoxicological Information

  • Ecotoxicological Information.001

  • Aquatic toxicity

    • Short-term toxicity to fish

      • Exp Key Short-term toxicity to fish.001

    • Long-term toxicity to fish

      • NS NS Long-term toxicity to fish.001

    • Short-term toxicity to aquatic invertebrates

      • Exp Key Short-term toxicity to aquatic invertebrates.001

    • Long-term toxicity to aquatic invertebrates

      • Exp Key Long-term toxicity to aquatic invertebrates.001

    • Toxicity to aquatic algae and cyanobacteria

      • Exp Key Toxicity to aquatic algae and cyanobacteria.001

    • Toxicity to microorganisms

      • Exp Key Toxicity to microorganisms.001

  • Sediment toxicity

    • NS NS Sediment toxicity.001

  • Terrestrial toxicity

    • Toxicity to soil macroorganisms except arthropods

      • NS NS Toxicity to soil macroorganisms except arthropods.001

    • Toxicity to terrestrial arthropods

      • NS NS Toxicity to terrestrial arthropods.001

    • Toxicity to terrestrial plants

      • NS NS Toxicity to terrestrial plants.001

    • Toxicity to soil microorganisms

      • NS NS Toxicity to soil microorganisms.001

    • Toxicity to birds

      • NS NS Toxicity to birds.001

• Toxicological information

  • Toxicological information.001

  • Toxicokinetics, metabolism and distribution

    • Basic toxicokinetics

      • Exp Key Basic toxicokinetics.001
      • Other Supporting Basic toxicokinetics.002
      • Other Supporting Basic toxicokinetics.003
      • Other Supporting Basic toxicokinetics.004
      • Other Supporting Basic toxicokinetics.005
      • Other Supporting Basic toxicokinetics.006

    • Dermal absorption

      • Other Supporting Dermal absorption.001

  • Acute Toxicity

    • Acute toxicity: oral

      • Exp Key Acute toxicity: oral.001

    • Acute toxicity: inhalation

      • NS NS Acute toxicity: inhalation.001

    • Acute toxicity: dermal

      • Exp Key Acute toxicity: dermal.001

  • Irritation / corrosion

    • Skin irritation / corrosion

      • Exp Key Skin irritation / corrosion.001

    • Eye irritation

      • Exp Key Eye irritation.001
      • Exp Supporting Eye irritation.002
      • Other Supporting Eye irritation.003

  • Sensitisation

    • Skin sensitisation

      • Exp Key Skin sensitisation.001

  • Repeated dose toxicity

    • Repeated dose toxicity: oral

      • Exp Key Repeated dose toxicity: oral.001

  • Genetic toxicity

    • Genetic toxicity in vitro

      • Exp Key Genetic toxicity in vitro.001
      • Exp Key Genetic toxicity in vitro.002
      • Other Supporting Genetic toxicity in vitro.003
      • Other Supporting Genetic toxicity in vitro.004
      • Other Supporting Genetic toxicity in vitro.005
      • Other Supporting Genetic toxicity in vitro.006
      • Other Supporting Genetic toxicity in vitro.007
      • Other Supporting Genetic toxicity in vitro.008
      • Other Supporting Genetic toxicity in vitro.009
      • Other Supporting Genetic toxicity in vitro.010

    • Genetic toxicity in vivo

      • Other Supporting Genetic toxicity in vivo.001
      • Other Supporting Genetic toxicity in vivo.002

  • Carcinogenicity

    • Exp Key Carcinogenicity.001
    • Other Supporting Carcinogenicity.002
    • Other Supporting Carcinogenicity.003

  • Toxicity to reproduction

    • Toxicity to reproduction

      • Exp Key Toxicity to reproduction.001

    • Developmental toxicity / teratogenicity

      • NS NS Developmental toxicity / teratogenicity.001

• Guidance on safe use

  • Guidance on safe use.001
  • (JS Member) Guidance on safe use.002
  • (JS Member) Guidance on safe use.003
  • (JS Member) Guidance on safe use.004

• Reference substances

  • 4,4'-methylenebis[2-chloroaniline]
  • 4,4'-methylenebis[2-chloroaniline]
  • 4,4'-methylenebis[2-chloroaniline]
  • 4,4'-methylenebis[2-chloroaniline]
  • 4,4'-methylenebis[2-chloroaniline]
  • 4,4'-methylenebis[2-chloroaniline]

• Identification
• Registration data
• Administrative data