p-cresol

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• General Information

  • Identification

  • Compositions

    • p-Cresol
    • p-cresol
    • p-Cresol
    • p-cresol
    • p-cresol 
    • Cresol, para
    • p-cresol

• Classification and Labelling

  • GHS

    • p-Cresol self-classification according to 2nd ATP
    • p-Cresol legal classificaton

  • DSD - DPD

    • classification of p-cresol

• Manufacture, Use & Exposure

  • Identified uses
  • Uses advised against

• PBT assessment

  • (JS Member) PBT assessment.001
  • (JS Member) PBT assessment.002

• Physical and chemical properties

  • Appearance/physical state/colour

    • Exp Key Appearance/physical state/colour.001

  • Melting point/freezing point

    • Exp Key Melting point/freezing point.001
    • Exp NS Melting point/freezing point.002
    • Exp Supporting Melting point/freezing point.003

  • Boiling point

    • Exp Key Boiling point.001
    • Exp NS Boiling point.002
    • Exp Supporting Boiling point.003
    • Exp Supporting Boiling point.004

  • Density

    • Exp Key Density.001
    • Exp Supporting Density.002
    • Exp Supporting Density.003
    • Exp Supporting Density.004

  • Particle size distribution (Granulometry)

    • NS NS Particle size distribution (Granulometry).001

  • Vapour pressure

    • Exp Key Vapour pressure.001
    • Exp NS Vapour pressure.002
    • Exp NS Vapour pressure.003
    • Exp Supporting Vapour pressure.004
    • Exp Supporting Vapour pressure.005

  • Partition coefficient

    • Exp Key Partition coefficient.001
    • Exp NS Partition coefficient.002
    • Exp Supporting Partition coefficient.003

  • Water solubility

    • Exp Key Water solubility.001
    • Exp NS Water solubility.002
    • Exp Supporting Water solubility.003
    • Exp Supporting Water solubility.004

  • Surface tension

    • NS NS Surface tension.001

  • Flash point

    • Exp Key Flash point.001

  • Auto flammability

    • Exp Key Auto flammability.001

  • Flammability

    • NS NS Flammability.001

  • Explosiveness

    • NS NS Explosiveness.001

  • Oxidising properties

    • NS NS Oxidising properties.001

  • Stability in organic solvents and identity of relevant degradation products

    • NS NS Stability in organic solvents and identity of relevant degradation products.001

  • Dissociation constant

    • Exp Key Dissociation constant.001
    • Exp NS Dissociation constant.002
    • Exp NS Dissociation constant.003
    • Exp Supporting Dissociation constant.004

  • Viscosity

    • NS NS Viscosity.001

  • Additional physico-chemical information

    • Exp NS Additional physico-chemical information.001
    • Exp NS Additional physico-chemical information.002
    • No data NS Additional physico-chemical information.003

• Environmental fate and pathways

  • Stability

    • Phototransformation in air

      • Exp Key Phototransformation in air.001
      • Exp Key Phototransformation in air.002
      • Exp Supporting Phototransformation in air.003
      • Exp Supporting Phototransformation in air.004
      • QSAR Supporting Phototransformation in air.005

    • Hydrolysis

      • NS NS Hydrolysis.001

    • Phototransformation in water

      • Exp Key Phototransformation in water.001
      • Exp NS Phototransformation in water.002
      • Exp NS Phototransformation in water.003
      • Exp Supporting Phototransformation in water.004

  • Biodegradation

    • Biodegradation in water: screening tests

      • Exp Key Biodegradation in water: screening tests.001
      • Exp Key Biodegradation in water: screening tests.002
      • Exp Key Biodegradation in water: screening tests.003
      • Exp Key Biodegradation in water: screening tests.004
      • Exp Key Biodegradation in water: screening tests.005
      • Exp Key Biodegradation in water: screening tests.006
      • Exp NS Biodegradation in water: screening tests.007
      • Exp NS Biodegradation in water: screening tests.008
      • Exp NS Biodegradation in water: screening tests.009
      • Exp NS Biodegradation in water: screening tests.010
      • Exp NS Biodegradation in water: screening tests.011
      • Exp Supporting Biodegradation in water: screening tests.012
      • Exp Supporting Biodegradation in water: screening tests.013
      • Exp Supporting Biodegradation in water: screening tests.014
      • Exp Supporting Biodegradation in water: screening tests.015
      • Exp Supporting Biodegradation in water: screening tests.016
      • Exp Supporting Biodegradation in water: screening tests.017
      • Exp Supporting Biodegradation in water: screening tests.018
      • Exp Supporting Biodegradation in water: screening tests.019
      • Exp Supporting Biodegradation in water: screening tests.020
      • Exp Supporting Biodegradation in water: screening tests.021
      • Exp Supporting Biodegradation in water: screening tests.022
      • Exp Supporting Biodegradation in water: screening tests.023
      • Exp Supporting Biodegradation in water: screening tests.024
      • Exp Supporting Biodegradation in water: screening tests.025
      • Exp Supporting Biodegradation in water: screening tests.026
      • Exp Supporting Biodegradation in water: screening tests.027
      • Exp Supporting Biodegradation in water: screening tests.028

    • Biodegradation in water and sediment: simulation tests

      • Exp Key Biodegradation in water and sediment: simulation tests.001
      • Exp Key Biodegradation in water and sediment: simulation tests.002
      • Exp Key Biodegradation in water and sediment: simulation tests.003
      • Exp Key Biodegradation in water and sediment: simulation tests.004
      • Exp Supporting Biodegradation in water and sediment: simulation tests.005
      • Exp Supporting Biodegradation in water and sediment: simulation tests.006

    • Biodegradation in soil

      • Exp Key Biodegradation in soil.001
      • Exp NS Biodegradation in soil.002
      • Exp NS Biodegradation in soil.003
      • Exp NS Biodegradation in soil.004

  • Bioaccumulation

    • Bioaccumulation: aquatic / sediment

      • Exp NS Bioaccumulation: aquatic / sediment.001
      • Read across Subs Key Bioaccumulation: aquatic / sediment.002
      • Read across Subs Key Bioaccumulation: aquatic / sediment.003

  • Transport and distribution

    • Adsorption / desorption

      • Exp Key Adsorption / desorption.001
      • Exp NS Adsorption / desorption.002
      • Exp NS Adsorption / desorption.003
      • Exp Supporting Adsorption / desorption.004
      • QSAR NS Adsorption / desorption.005

    • Henry's Law constant

      • Exp Key Henry's Law constant.001
      • Exp Supporting Henry's Law constant.002

    • Distribution modelling

      • QSAR Key Distribution modelling.001

  • Environmental data

    • Monitoring data

      • Other NS Monitoring data.001

  • Additional information on environmental fate and behaviour

    • Other NS Additional information on environmental fate and behaviour.001

• Ecotoxicological Information

  • Ecotoxicological Information.001

  • Aquatic toxicity

    • Short-term toxicity to fish

      • Exp Key Short-term toxicity to fish.001
      • Exp NS Short-term toxicity to fish.002
      • Exp NS Short-term toxicity to fish.003
      • Exp NS Short-term toxicity to fish.004
      • Exp NS Short-term toxicity to fish.005
      • Exp Supporting Short-term toxicity to fish.006
      • Exp Supporting Short-term toxicity to fish.007
      • Exp Supporting Short-term toxicity to fish.008
      • Exp Supporting Short-term toxicity to fish.009
      • Exp Supporting Short-term toxicity to fish.010
      • Exp Supporting Short-term toxicity to fish.011
      • Exp Supporting Short-term toxicity to fish.012
      • Exp Supporting Short-term toxicity to fish.013
      • Exp Supporting Short-term toxicity to fish.014
      • Other NS Short-term toxicity to fish.015
      • Other NS Short-term toxicity to fish.016
      • Other NS Short-term toxicity to fish.017

    • Long-term toxicity to fish

      • Exp Key Long-term toxicity to fish.001
      • Exp NS Long-term toxicity to fish.002

    • Short-term toxicity to aquatic invertebrates

      • Exp Key Short-term toxicity to aquatic invertebrates.001
      • Exp Key Short-term toxicity to aquatic invertebrates.002
      • Exp NS Short-term toxicity to aquatic invertebrates.003
      • Exp NS Short-term toxicity to aquatic invertebrates.004
      • Exp NS Short-term toxicity to aquatic invertebrates.005
      • Exp NS Short-term toxicity to aquatic invertebrates.006
      • Exp Supporting Short-term toxicity to aquatic invertebrates.007

    • Long-term toxicity to aquatic invertebrates

      • Exp Key Long-term toxicity to aquatic invertebrates.001
      • Exp Key Long-term toxicity to aquatic invertebrates.002

    • Toxicity to aquatic algae and cyanobacteria

      • Exp Key Toxicity to aquatic algae and cyanobacteria.001
      • Exp NS Toxicity to aquatic algae and cyanobacteria.002
      • Exp NS Toxicity to aquatic algae and cyanobacteria.003
      • Exp NS Toxicity to aquatic algae and cyanobacteria.004
      • Exp NS Toxicity to aquatic algae and cyanobacteria.005
      • Exp NS Toxicity to aquatic algae and cyanobacteria.006

    • Toxicity to aquatic plants other than algae

      • Exp NS Toxicity to aquatic plants other than algae.001
      • Exp NS Toxicity to aquatic plants other than algae.002
      • Exp NS Toxicity to aquatic plants other than algae.003
      • NS NS Toxicity to aquatic plants other than algae.004

    • Toxicity to microorganisms

      • Exp Key Toxicity to microorganisms.001
      • Exp Key Toxicity to microorganisms.002
      • Exp Key Toxicity to microorganisms.003
      • Exp Key Toxicity to microorganisms.004
      • Exp NS Toxicity to microorganisms.005
      • Exp NS Toxicity to microorganisms.006
      • Exp NS Toxicity to microorganisms.007
      • Exp NS Toxicity to microorganisms.008
      • Exp NS Toxicity to microorganisms.009
      • Exp NS Toxicity to microorganisms.010
      • Exp NS Toxicity to microorganisms.011
      • Exp NS Toxicity to microorganisms.012
      • Exp Supporting Toxicity to microorganisms.013
      • Exp Supporting Toxicity to microorganisms.014

  • Sediment toxicity

    • NS NS Sediment toxicity.001

  • Terrestrial toxicity

    • Toxicity to soil macroorganisms except arthropods

      • NS NS Toxicity to soil macroorganisms except arthropods.001

    • Toxicity to terrestrial arthropods

      • NS NS Toxicity to terrestrial arthropods.001

    • Toxicity to terrestrial plants

      • Exp NS Toxicity to terrestrial plants.001
      • Exp NS Toxicity to terrestrial plants.002
      • Exp NS Toxicity to terrestrial plants.003
      • Exp Supporting Toxicity to terrestrial plants.004
      • Other NS Toxicity to terrestrial plants.005
      • Read across Subs Key Toxicity to terrestrial plants.006

    • Toxicity to soil microorganisms

      • Exp NS Toxicity to soil microorganisms.001
      • NS NS Toxicity to soil microorganisms.002

    • Toxicity to birds

      • Exp NS Toxicity to birds.001
      • NS NS Toxicity to birds.002

• Toxicological information

  • Toxicological information.001

  • Toxicokinetics, metabolism and distribution

    • Basic toxicokinetics

      • Exp NS Basic toxicokinetics.001
      • Exp NS Basic toxicokinetics.002
      • Exp NS Basic toxicokinetics.003
      • NS NS Basic toxicokinetics.004
      • NS NS Basic toxicokinetics.005
      • NS NS Basic toxicokinetics.006
      • Other NS Basic toxicokinetics.007
      • Other NS Basic toxicokinetics.008

    • Dermal absorption

      • Exp NS Dermal absorption.001

  • Acute Toxicity

    • Acute toxicity: oral

      • Exp Key Acute toxicity: oral.001
      • Exp NS Acute toxicity: oral.002
      • Exp NS Acute toxicity: oral.003
      • Exp NS Acute toxicity: oral.004
      • Exp NS Acute toxicity: oral.005
      • Exp NS Acute toxicity: oral.006

    • Acute toxicity: inhalation

      • Exp Supporting Acute toxicity: inhalation.001
      • Exp Supporting Acute toxicity: inhalation.002
      • NS NS Acute toxicity: inhalation.003

    • Acute toxicity: dermal

      • Exp Key Acute toxicity: dermal.001
      • Exp NS Acute toxicity: dermal.002
      • Exp NS Acute toxicity: dermal.003
      • NS NS Acute toxicity: dermal.004

    • Acute toxicity: other routes

      • Exp NS Acute toxicity: other routes.001
      • Exp NS Acute toxicity: other routes.002

  • Irritation / corrosion

    • Skin irritation / corrosion

      • Exp Key Skin irritation / corrosion.001
      • Exp Supporting Skin irritation / corrosion.002

    • Eye irritation

      • Exp Key Eye irritation.001
      • Other NS Eye irritation.002

  • Sensitisation

    • Skin sensitisation

      • Exp Key Skin sensitisation.001
      • NS NS Skin sensitisation.002

  • Repeated dose toxicity

    • Repeated dose toxicity: oral

      • Exp Key Repeated dose toxicity: oral.001
      • Exp NS Repeated dose toxicity: oral.002
      • Exp NS Repeated dose toxicity: oral.003
      • Exp NS Repeated dose toxicity: oral.004
      • Read across Cat Supporting Repeated dose toxicity: oral.005
      • Read across Cat Supporting Repeated dose toxicity: oral.006

    • Repeated dose toxicity: inhalation

      • Exp NS Repeated dose toxicity: inhalation.001
      • NS NS Repeated dose toxicity: inhalation.002

    • Repeated dose toxicity: dermal

      • Exp NS Repeated dose toxicity: dermal.001
      • Exp NS Repeated dose toxicity: dermal.002
      • NS NS Repeated dose toxicity: dermal.003

  • Genetic toxicity

    • Genetic toxicity in vitro

      • Exp Key Genetic toxicity in vitro.001
      • Exp Key Genetic toxicity in vitro.002
      • Exp Key Genetic toxicity in vitro.003
      • Exp NS Genetic toxicity in vitro.004
      • Exp NS Genetic toxicity in vitro.005
      • Exp NS Genetic toxicity in vitro.006
      • Exp NS Genetic toxicity in vitro.007
      • Exp NS Genetic toxicity in vitro.008
      • Exp NS Genetic toxicity in vitro.009
      • Exp NS Genetic toxicity in vitro.010
      • Exp NS Genetic toxicity in vitro.011
      • Exp NS Genetic toxicity in vitro.012
      • Exp Supporting Genetic toxicity in vitro.013

    • Genetic toxicity in vivo

      • Exp Key Genetic toxicity in vivo.001
      • Exp NS Genetic toxicity in vivo.002
      • Exp NS Genetic toxicity in vivo.003
      • Read across Subs Supporting Genetic toxicity in vivo.004

  • Carcinogenicity

    • Exp NS Carcinogenicity.001
    • Exp NS Carcinogenicity.002
    • Exp NS Carcinogenicity.003
    • Read across Subs Key Carcinogenicity.004
    • Read across Subs Key Carcinogenicity.005

  • Toxicity to reproduction

    • Toxicity to reproduction

      • Exp Key Toxicity to reproduction.001

    • Developmental toxicity / teratogenicity

      • Exp Key Developmental toxicity / teratogenicity.001
      • Exp Supporting Developmental toxicity / teratogenicity.002

    • Toxicity to reproduction: other studies

      • Exp NS Toxicity to reproduction: other studies.001
      • NS NS Toxicity to reproduction: other studies.002

  • Specific investigations

    • Neurotoxicity

      • Exp Key Neurotoxicity.001

  • Exposure related observations in humans

    • Health surveillance data

      • NS Key Health surveillance data.001
      • Other NS Health surveillance data.002

    • Direct observations: clinical cases, poisoning incidents and other

      • NS NS Direct observations: clinical cases, poisoning incidents and other.001
      • NS NS Direct observations: clinical cases, poisoning incidents and other.002
      • NS NS Direct observations: clinical cases, poisoning incidents and other.003
      • NS NS Direct observations: clinical cases, poisoning incidents and other.004
      • NS NS Direct observations: clinical cases, poisoning incidents and other.005
      • NS NS Direct observations: clinical cases, poisoning incidents and other.006
      • Other NS Direct observations: clinical cases, poisoning incidents and other.007
      • Other NS Direct observations: clinical cases, poisoning incidents and other.008
      • Other NS Direct observations: clinical cases, poisoning incidents and other.009
      • Other NS Direct observations: clinical cases, poisoning incidents and other.010
      • Other NS Direct observations: clinical cases, poisoning incidents and other.011
      • Other NS Direct observations: clinical cases, poisoning incidents and other.012
      • Other NS Direct observations: clinical cases, poisoning incidents and other.013

    • Sensitisation data (humans)

      • Exp Supporting Sensitisation data (humans).001

    • Exposure related observations in humans: other data

      • Exp Key Exposure related observations in humans: other data.001
      • Exp Key Exposure related observations in humans: other data.002

  • Additional toxicological information

    • Exp NS Additional toxicological information.001
    • Exp NS Additional toxicological information.002
    • Exp NS Additional toxicological information.003
    • Exp NS Additional toxicological information.004
    • Exp NS Additional toxicological information.005
    • Exp NS Additional toxicological information.006
    • Exp NS Additional toxicological information.007
    • Exp NS Additional toxicological information.008
    • Exp NS Additional toxicological information.009
    • Exp NS Additional toxicological information.010
    • Exp NS Additional toxicological information.011
    • Exp NS Additional toxicological information.012
    • Exp NS Additional toxicological information.013
    • Exp NS Additional toxicological information.014
    • Exp NS Additional toxicological information.015
    • Exp NS Additional toxicological information.016
    • NS NS Additional toxicological information.017
    • Other NS Additional toxicological information.018
    • Other NS Additional toxicological information.019
    • Other NS Additional toxicological information.020
    • Other NS Additional toxicological information.021
    • Other NS Additional toxicological information.022

• Guidance on safe use

  • Guidance on safe use.001
  • (JS Member) Guidance on safe use.002
  • (JS Member) Guidance on safe use.003
  • (JS Member) Guidance on safe use.004
  • (JS Member) Guidance on safe use.005
  • (JS Member) Guidance on safe use.006

• Reference substances

  • 6-tert-butyl-m-cresol
  • 3,5-xylenol
  • phenol
  • p-cresol
  • p-cresol
  • o-cresol
  • p-cresol
  • 2,4-xylenol
  • m-cresol
  • p-cresol
  • p-cresol